DELAYED GADOLINIUM-ENHANCED MRI OF - Dissertations.se

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PMID: 27568543 [Indexed for MEDLINE] Sammanfattningsvis ter sig dGEMRIC mycket lovande för att öka kunskapen om artrossjukdomens tidiga skeden samt för utvärdering av olika behandlingsfor-mer. Carl Johan Tiderius carl-johan.tiderius@skane.se Avhandling. Carl-Johan Tiderius. Contrast-enhanced MRI of human knee cartilage-clinical applications of the novel dGEMRIC technique to T1 - Current knowledge and importance of dGEMRIC techniques in diagnosis of hip joint diseases.

Carl Johan Tiderius carl-johan.tiderius@skane.se Avhandling. Carl-Johan Tiderius. Contrast-enhanced MRI of human knee cartilage-clinical applications of the novel dGEMRIC technique to T1 - Current knowledge and importance of dGEMRIC techniques in diagnosis of hip joint diseases. AU - Zilkens, Christoph.

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The dGEMRIC technique is based on the electrical polarity of gadolinium [Gd (DPTA)2− ions] and glycosaminoglycans in the joint. Traditionally dGEMRIC has been performed using a two-dimensional T1-weighted inversion recovery (2D-IR) sequence to acquire data for quantitative T1 mapping [ 18, 19 ]. The major advantage of this method is the widespread availability of the sequence and desirable contrast properties (cartilage versus fluid).

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Melkus, Gerd PhD Herein, we describe the dGEMRIC technique using a new positively charged contrast agent (i.e. dGEMRIC+). Specifically, we report: the synthesis and Methods: dGEMRIC, T2 and native T1 relaxation times of healthy mature human, juvenile porcine technique for reliable assessment of the cartilage PG con-. Nov 10, 2016 Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) allows an dGEMRIC provides a non-invasive method of assessing these effects. Methods.

Using this technique, the distribution of Gd-(DTPA) 2− contrast agent in cartilage after intravenous injection is assessed with quantitative T 1 mapping. Compositional assessment techniques include T2 mapping, delayed gadolinium-enhanced MR imaging of cartilage (dGEMRIC), T1ρ imaging, sodium imaging, and diffusion-weighted imaging.
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Materials and methods. We examined the effect of stainless-steel and titanium hardware on dGEMRIC T 1 maps. We tested two strategies to reduce metal artifact in dGEMRIC: (1) saturation recovery (SR) instead of inversion recovery (IR) and (2) applying the metal artifact reduction sequence (MARS), in a gadolinium-doped agarose gel phantom and in vivo with titanium hardware. The dGEMRIC technique is a potentially useful clinical imaging method that is currently limited by the long imaging time and need for post‐processing.

dGEMRIC requires intravenous injection of gadolinium contrast, however, which adds time, expense, and 2013-07-01 2013-12-20 Purpose: To determine the feasibility of using a high resolution isotropic three-dimensional (3D) fast T1 mapping sequence for delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) to assess osteoarthritis in the hip. The delayed Gadolinium Enhanced Magnetic Resonance Imaging of Cartilage (dGEMRIC) technique is a well- established method for early assessment of cartilage quality in osteoarthritis.
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Autologous chondrocyte implantation in cartilage lesions of

Hence, the dGEMRIC technique holds promise for the development of new diagnostic and therapeutic procedures. However, because of the location of the hip joint deep within the body and due to the fairly thin cartilage layers that require high spatial resolution, the diagnosis of early hip joint cartilage alterations may be problematic. Delayed contrast-enhanced MRI of cartilage (dGEMRIC) is a noninvasive technique to study cartilage glycosaminoglycan (GAG) content in vivo.

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In this study, T 2 mapping and dGEMRIC techniques were used to evaluate cartilage repair approximately 1 year after dict.cc | Übersetzungen für 'delayed gadolinium enhanced MRI of cartilage technique dGEMRIC technique' im Schwedisch-Deutsch-Wörterbuch, mit echten Sprachaufnahmen, Illustrationen, Beugungsformen, Se hela listan på academic.oup.com 2011-11-24 · The dGEMRIC index has been validated against histologic and biochemical measurements of glycosaminoglycan content in clinical studies . dGEMRIC has potential as a non-invasive technique for monitoring the glycosaminoglycan content of cartilage after repair by various techniques (Figure 6). inium contrast, however, which adds time, expense, and possible adverse reactions to the imaging procedure. Newer MRI cartilage mapping techniques such as T1 rho (ρ) and T2* have been performed in the hip without the need for any contrast, although it is unknown whether they are equivalent to dGEMRIC. Question/purpose In this study, our purpose was to determine the correlation between the Biochemical MRI With dGEMRIC Corresponds to 3D-CT Based Impingement (MRI) techniques are limited and can detect macroscopic chondral damage.4,41,51,59 The ability to dGEMRIC is a biochemical imaging technique that can assess the charge density of cartilage. Cartilage can respond to increased mechanical loading by increasing charge density.